Safety and efficacy of a high-adhesion whitening strip under extended wear regimen | jodjournal.com

Gustavo M. Oliveira, Patricia A. Miguez, Greice B. Oliveira, Edward J. Swift Jr., Svetlana Farrell, Mary Kay Anastasia, Erinn Conde, Ricardo Walter

This randomized, parallel group, single centre clinical trial was conducted to evaluate the safety and compare the whitening efficacy for an extended wear of an experimental 9.5% H2O2 high-adhesion whitening strip, relative to a marketed 10% H2O2 control strip.

Methods

Twenty-nine eligible adult volunteers were randomly assigned to either a treatment series with an experimental 9.5% H2O2 high-adhesion whitening strip at home for 2h, once a day, for 8 days; or a marketed 10% H2O2 whitening strip for 30min, on a similar daily regimen. Tooth colour/whitening progression was recorded under standardized lighting conditions at baseline, day 3, day 5, and day 9, via digital imaging. Outcomes were reported using the CIELAB system. Usage safety was also assessed at each follow-up visit. Whitening efficacy for each group was investigated using a paired-difference t-test. The treatment groups were compared among each other using the analysis of covariance, with the baseline value and age as the covariates.

read more at  Safety and efficacy of a high-adhesion whitening strip under extended wear regimen.

Leave a Reply

Your email address will not be published. Required fields are marked *

You may use these HTML tags and attributes: <a href="" title=""> <abbr title=""> <acronym title=""> <b> <blockquote cite=""> <cite> <code> <del datetime=""> <em> <i> <q cite=""> <strike> <strong>